Search Result

Search Results for " mitogen-activated protein kinase kinase 6 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T16501	PF-3644022		p38 MAPK , Serine Protease , MAPK
	PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFα production and has an anti-inflammatory effect. PF-3644022 also inhib...		p38 MAPK , Serine Protease , MAPK
T12781	RV01		Others
	RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...		Others
T37739	N-decanoyl-L-Homoserine lactone	C10-HSL,N-decanoyl-L-Homoserine lactone	Reactive Oxygen Species , Antibacterial
	N-decanoyl-L-Homoserine lactone (C10-HSL) is an N-acyl-homoserine lactone (AHL) produced by Pseudomonas cremoris strain ND07.N-decanoyl-L-homoserine lactone inhibits the growth of primary roots of Arabidopsis thaliana.N-...		Reactive Oxygen Species , Antibacterial
T76242	MMI-0100
	MMI-0100, a cell-permeant peptide inhibitor of mitogen-activated protein kinase activated protein kinase II (MK2), effectively reduces intimal hyperplasia ex vivo and in vivo. It specifically suppresses IL-6 expression w...
T69451	R-130823
	R-130823 is a ighly selective inhibition against mitogen-activated protein kinase p38alpha (IC50=22 nM). The release of tumor necrosis factor-alpha, interleukin-1beta, -6 and -8 was inhibited in lipopolysaccharide-stimul...
T35593	Semapimod tetrahydrochloride	CPSI-2364 tetrahydrochloride	TLR , MAPK
	Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a synthetic ornithine mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor that interferes with macrophage and microgl...		TLR , MAPK

Compounds

PF-3644022

T16501

Synonym:

Target: p38 MAPK, Serine Protease, MAPK

N-decanoyl-L-Homoserine lactone

T37739

Synonym: C10-HSL,N-decanoyl-L-Homoserine lactone

Target: Reactive Oxygen Species, Antibacterial

Semapimod tetrahydrochloride

T35593

Synonym: CPSI-2364 tetrahydrochloride

Target: TLR, MAPK

Cat No.	Product Name	Synonyms	Targets
T3816	Velutin		NF-κB , HIF/HIF Prolyl-Hydroxylase
	Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as in inhibiting mitogen-activated protein kinase p38 and JNK ...		NF-κB , HIF/HIF Prolyl-Hydroxylase
TN1410	Asperulosidic acid	ASPA	ERK , NF-κB
	Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...		ERK , NF-κB
T6S1369	Vitexin	Apigenin-8-C-glucoside	Antioxidant
	1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...		Antioxidant
T6S1684	8-Gingerol		Antioxidant , Antibacterial , TRP/TRPV Channel
	1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...		Antioxidant , Antibacterial , TRP/TRPV Channel

Natural Products

Velutin

T3816

Synonym:

Target: NF-κB, HIF/HIF Prolyl-Hydroxylase

Synonym: Apigenin-8-C-glucoside

Target: Antioxidant, Antibacterial, TRP/TRPV Channel

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04365	MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)	Human	Baculovirus Insect Cells
	MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
TMPY-04748	MKK6 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	MKK6 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 37.6 kDa and the accession number is A8K3Y2.
TMPY-04749	MKK6 Protein, Human, Recombinant (S207D, T211D)	Human	Baculovirus Insect Cells
	MKK6 Protein, Human, Recombinant (S207D, T211D) is expressed in Baculovirus insect cells. The predicted molecular weight is 37.7 kDa and the accession number is P52564-1.
TMPY-04364	MKK6 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	MKK6 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
TMPY-04430	P38 gamma/MAPK12 Protein, Human, Recombinant	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 42.1 kDa and the accession number is P53778.
TMPY-04429	P38 gamma/MAPK12 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	p38 gamma/MAPK12 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69.8 kDa and the accession number is P53778.
TMPY-02595	DUSP14 Protein, Human, Recombinant (His & MBP)	Human	E. coli
	Dual specific phosphatase 14 / MAP-kinase phophatase-6 (DUSP14 / MKP6) is a member of Dual-specificity phosphatases that is a subclass of protein tyrosine phosphatases (PTP) families that can dephosphorylate bothe phosph...
TMPY-03010	NRG1 beta 1 Protein, Human, Recombinant	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPY-02705	NRG1 beta 1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPY-04277	CD45 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPJ-00827	Tau-D Protein, Human, Recombinant (His)	Human	E. coli
	Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPK-00614	NKp46/NCR1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPK-00615	NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPY-03128	LAIR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPY-02600	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)	Human	HEK293 Cells
	NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-05798	VEGF145 Protein, Human, Recombinant	Human	HEK293 Cells
	VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPJ-00567	NCR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPK-01364	SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01358	SIRP alpha V6 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...